More than 300 days of sunshine annually (more than San Diego or Miami Beach) earns Denver high marks with visitors and make sunglasses a must. For the city's most energetic shopping, dining and entertainment spots, point your compass in the direction of Larimer Square, the Tivoli, LoDo and the 16th Street Mall.

Bolzano, nestled in the Italian Alps, offers a unique blend of Italian charm and Austrian influence. This picturesque city is a gateway to the Dolomites, a UNESCO World Heritage site known for its dramatic mountain peaks and scenic beauty. Visitors can explore the stunning medieval architecture of the Bolzano Cathedral, with its intricate Gothic details and colorful tiled roof.

An essential passageway between the Atlantic and Pacific Oceans, the Panama Canal is an extraordinary technological landmark and a testament to human innovation. Built in the early twentieth century by American engineers, the canal weaves through the Panamanian isthmus and allows easy access for commercial freighters and cruise ships alike.

Windswept beaches, verdant forests and snow-capped peaks give way to sweeping rangelands, towering rock formations and dramatic river valleys in this incredibly diverse land.

Manaus, the capital of Brazil's Amazonas, is a major entryway to the vast and biodiverse Amazon Rainforest. Situated on both the Rio Negro and Amazon River, this city will charm you with Renaissance-style buildings and a variety of city parks, museums, and theatres.